What Neurological Disorders Can CBD Help Treat?

How CBD Can Help Treat Certain Neurological Disorders

Within our bodies is the endocannabinoid system, a complex network of neurotransmitters with cannabinoid receptors. While our bodies make molecules compatible to these receptors, called endogenous cannabinoids, it’s easy for this system to become depleted. Once low in cannabinoids, the affected organs and other bodily systems dependent on the endocannabinoid system’s signaling will begin to function at a lower capacity. 

Because the endocannabinoid system exists within the central and peripheral nervous systems, boosting it through external cannabinoids can help treat various disorders, especially those associated with the nervous system. Cannabinoids made by plants, called phytocannabinoids, are found in cannabis. CBD and THC are both types of phytocannabinoids, though CBD offers all the same benefits of THC without the intoxicating psychoactive effects. CBD oil can therefore treat many people experiencing neurological disorders without impacting their other medications or daily life! Read on to see how.

CBD’s Overall Impact on the Nervous System

Research on CBD has been ongoing for decades, but scientists are close to solidifying its remarkable effects on the body. These results are doubly true for those with neurological disorders or other disorders, because CBD tends to have a greater effect on those with underlying or current conditions. Here are some of the main cells in the nervous system, and how CBD affects them.

CBD’s Influence on Neurons

Neurons are the cells found in the nervous system, both central (brain and spinal cord) as well as peripheral (bodily neurons). Neurons work to transmit messages in the form of electrical impulses, and it’s how your brain communicates not only with the body but also with itself. Many neurological disorders are centered around the death or dysfunction of neurons, resulting in incorrect or nonexistent communication within parts of the neural network.

CBD plays a huge role in influencing neuron behavior and function by increasing anandamide, PPARy, and apoptosis. Anandamide is responsible for homeostatic regulation, and helps improve neuron signaling while reducing inflammation. PPARy stands for peroxisome proliferator-activated receptor, which allows cells to better transcribe their genes when up-regulated by CBD. Apoptosis is the process by which old, sick, or infected cells kill themselves to avoid spreading disease or damage. It’s a vital resource to the body, and allows your body to fight many diseases and disorders every day.

CBD also acts as an antioxidant for neuroprotection, reducing free radicals near or in cells to decrease oxidative stress and permanent cellular damage. 

Lastly, CBD improves plasticity and brain-derived neurotrophic factor (BDNF). Plasticity is our brain’s ability to adapt and grow, and BDNF is critical for nerve growth and regeneration – both of which not only slow the effects of some neurological disorders but even repair damaged tissue.

CBD and Endothelial Cells

Endothelial cells are the cells that sit between vessels and tissue. They may be vascular endothelial cells, which are against blood vessels, or lymphatic endothelial cells, which are in direct contact with lymph. They are found all throughout the body including inside the brain and other nervous system parts.

In some neurological disorders, there is heightened blood pressure and inflammation in the brain. The high pressure can cause damaged blood vessels, inhibiting oxygen and nutrient distribution to the brain. Inflammation, when chronic and long-lasting, tends to cause damage to surrounding tissues, which is an extremely serious issue when neurons are involved. 

CBD affects endothelial cells by decreasing the amount of vascular cell adhesion protein 1 (VCAM-1) and reducing the pro-inflammatory cytokines. VCAM-1 is thought to be associated with brain aging and degradation, while pro-inflammatory cytokines will increase a body’s inflammatory response even when it’s detrimental to the tissues.

CBD’s Effects on Oligodendrocytes

Oligodendrocytes are neuroglia that provide support and insulation to the axons of the central nervous system. They’re responsible for creating and supporting the myelin sheath that runs along the length of the axon. 

When oligodendrocytes are damaged, serious complications follow. An example is in multiple sclerosis, where the cells in your body wrongfully attack the myelin sheath or the oligodendrocytes that support it. Without a myelin sheath, signals aren’t able to travel as quickly along the axon, inhibiting how nerves are capable of communicating and transmitting signals.

CBD can impact oligodendrocytes by decreasing endoplasmic reticulum stress, which allows cells to synthesize vital proteins more easily. It also acts as an antioxidant around oligodendrocytes, much like it does with neurons.

CBD’s Impact on Microglial Cells

Microglial cells have the special job of finding and removing damaged neurons and infections within the central nervous system. They can be especially important in reducing neuroinflammation, the oxidative stress of which can promote neurodegeneration. 

Neurodegeneration and neuroinflammation tend to be common symptoms of dementias, namely Alzheimer’s.

CBD decreases pro-inflammatory cytokines as well as pro-inflammatory mediators like NF-kB, which reduces the body’s ability to amount what would be considered an overreaction of the immune response. It also slows microglial cell migration, which can be helpful when these cells are being wrongfully activated, as they may remove neurons that are not damaged.

cannajoy’s All-Natural Hemp CBD Can Help

As you can see, CBD plays a major role in providing support for the beneficial systems in our brains, and inhibiting the processes that can result in damage when our bodies are experiencing a disorder. CBD is a phenomenal treatment addition for those experiencing dementia, Alzheimer’s, multiple sclerosis, Parkinson’s, malignant brain tumors, childhood seizure disorders, and even mood disorders. At cannajoy, we know that not all CBD is made equal, and you want to give your brain the best CBD available. Our line of CBD oils and CBD oil-infused products are made with your health in mind, and are organic and all-natural. Shop our selection of CBD online now to give your brain a boost!
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